Toluene → HCID 19814662, compound

Participants

Reaction Conditions

Reaction Steps

65.2 g of phenyl (N-ethylsulfonyl-N-methylamino)sulfonylcarbamate are dissolved in 700 ml of toluene, 36.6 g of 2-amino-4,6-diethoxypyrimidine are added at room temperature, and the mixture is heated at 110° C. for 2 hours. After cooling to room temperature, the precipitate is filtered at 0° C. and washed with 200 ml of toluene. 82.6 g of the desired product of a purity of 98.1% are obtained, which corresponds to a yield of 95.3% of theory.

Provenance & Evidence