Dimethylamine → 1-[4-(Dimethylamino)-2-butynyl]-2-imidazolidinone

HRID 466761Notes

Reaction equation

C[N:2]1[CH2:6][CH2:5][N:4]([CH2:7][C:8]#[CH:9])[C:3]1=[O:10].[CH3:11][NH:12][CH3:13].N1CCC[CH2:15]1>>[CH3:11][N:12]([CH3:15])[CH2:13][C:9]#[C:8][CH2:7][N:4]1[CH2:5][CH2:6][NH:2][C:3]1=[O:10]

Participants

Reactant 3

HCID 674Dimethylamine

HCID 31268Pyrrolidine

HCID 113555131-Methyl-3-(2-propynyl)-2-imidazolidinone

Product 1

HCID 150655151-[4-(Dimethylamino)-2-butynyl]-2-imidazolidinone

Procedure

This product was prepared according to Example 1, Part B, by substituting 1-(2-propynyl)-2-imidazolidinone for 1-methyl-3-(2-propynyl)-2-imidazolidinone and dimethylamine for pyrrolidine; m.p. 83°-87° C.

Workup

customThis product was prepared

Sources & evidence

ORD record: ord-567399b0073e4c50a7928e0b89364246
Source dataset: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05157124

Reaction notes

Loading…