HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 70047169, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 478-88-6 | HCID 6857537 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 70047169 | HCID 70047169 | — |
Reaction Steps
1.0 mmol of ergoline is dissolved in 10 ml of glacial acetic acid. 5 ml (0.05 mol) of acetic anhydride and 0.8 g (0.01 mol) of anhydrous sodium acetate are added and allowed to stir overnight at room temperature. For working up, ice is added, it is stirred for 30 minutes and mixed with NH3 solution. After extraction with dichloromethane, drying of the organic phases on Na2SO4 and removal of the solvent in a vacuum, the raw product is obtained which is further purified by crystallization or chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05158957 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-b2c7a53c049c41f896b87cce567c05f8 |
| Source note | uspto-grants-1992_10 |