HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → 1-Dimethylaminosulfonyl-2-amino-6-(alpha-isopropylidenbenzyl)benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 1-Dimethylaminosulfonyl-2-amino-6-(alpha-isopropyl-alpha-hydroxybenzyl)benzimidazole | HCID 20490458 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-Dimethylaminosulfonyl-2-amino-6-(alpha-isopropylidenbenzyl)benzimidazole | HCID 20490457 | — |
Reaction Steps
When the procedure of Example 72 was repeated using 1.2 g. (3.2 mmoles) of 1-dimethylaminosulfonyl-2-amino-6-(α-isopropyl-α-hydroxybenzyl)benzimidazole, 750 mg. of p-toluenesulfonic acid, and 100 ml. of chloroform, there was obtained 1-dimethylaminosulfonyl-2-amino-6-(α-isopropylidenebenzyl)benzimidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04174454 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-c4b6d0ccb284400d850d8dcdb90094d1 |
| Source note | uspto-grants-1979_11 |