反应详情

A solution containing 54.0 g (0.385 mol) of 1-methylcyclopropanecarboxylic acid hydrazide (m.p. 72°-74°) and 90 g (0.9 mol) of phosgene in 1000 ml of ethyl acetate was refluxed for 2 hours. The reaction mixture was concentrated on a rotary evaporator. The residual solid crystallized from ether-hexane (1:5) to give 56.0 g (85%) of product as a white crystalline solid; m.p. 77°-78°.

1. temperaturewas refluxed for 2 hours
2. concentrationThe reaction mixture was concentrated on a rotary evaporator
3. customThe residual solid crystallized from ether-hexane (1:5)