Benzyloxycarbonyl-L-phenylalanine → N-Benzyloxycarbonylphenylalanylalanine

HRID 467298Notes

Reaction equation

HRID 467298 reaction equation
[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:20]([NH:22][C@H:23]([C:35]([OH:37])=[O:36])[CH2:24]CCCNC(=O)C(F)(F)F)=[O:21])[CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC(N[C@H](C(O)=O)CC1C=CC=CC=1)=O)C1C=CC=CC=1.FC(F)(F)C(NCCCC[C@@H](C(O)=O)N)=O>>[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:20]([NH:22][C@H:23]([C:35]([OH:37])=[O:36])[CH3:24])=[O:21])[CH2:13][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 70878Benzyloxycarbonyl-L-phenylalanineHCID 7009573L-Lysine, N6-(trifluoroacetyl)-HCID 15017706HCID 15017706, compound

Product 1

HCID 152128N-Benzyloxycarbonylphenylalanylalanine

Procedure

N-Benzyloxycarbonyl-L-phenylalanyl-Nε -trifluoroacetyl-L-lysine (m.p. 143°-147° C.) from N-benzyloxycarbonyl-L-phenylalanine and Nε -trifluoroacetyl-L-lysine (A. T. Moore, et al., J. Chem. Soc. (C), 2349-2359 (1966)).

Sources & evidence

ORD record
ord-1ff700a3d30140cbac83394822b20436
Source dataset
uspto-grants-1992_10
Patent number
US05158936

Reaction notes

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