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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 467360Generated: October 25, 2026

Dicyclohexylcarbodiimide → HCID 178427518, compound

https://huagongshe.com/reaction/467360

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDicyclohexylcarbodiimideHCID 10868—
ReactantN2-((tert-Butoxy)carbonyl)-L-asparagineHCID 82035—
Reactant3a,4,7,7a-Tetrahydro-2-hydroxy-4,7-methano-1H-isoindole-1,3(2H)-dioneHCID 89529—
ReactantHCID 178427520HCID 178427520—
ProductHCID 178427518HCID 178427518—

Reaction Steps

Using 2.20 g Boc-Ser(Bzl)-Phe-D-Arg(Tos)-Tyr(Bzl)-OBzl, 0.61 g Boc- Asn-OH, 0.51 g HONB and 0.58 g DCC, the desired product was obtained in exactly the same manner as in Example 1-(IV).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05159061
Source datasetuspto-grants-1992_10
ORD IDord-e3f5450518a243ccaaa742b0cf103a13
Source noteuspto-grants-1992_10