Phenylisohexanol → 3-Methyl-5-cyclohexylpentanol

HRID 467398Notes

Reaction equation

HRID 467398 reaction equation
[CH3:1][CH:2]([CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH2:3][CH2:4][OH:5].[H][H]>>[CH:8]1([CH2:7][CH2:6][CH:2]([CH3:1])[CH2:3][CH2:4][OH:5])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 108312PhenylisohexanolHCID 178418361HCID 178418361, compound

Product 1

HCID 212677663-Methyl-5-cyclohexylpentanolYield 99.7%

Procedure

1200 g of 3-Methyl-5-phenyl-pentanol (Phenoxanol™, supplier: IFF) combined with 10.5 g Ru on aluminium oxide (Ru content 5 wt. %) were hydrogenated at a hydrogen pressure of 25 bar and at a temperature of 110° C. After 15 hours the reaction was finished. The catalyst was removed and the product distilled. 1204 g (content 99.7%) of 5-cyclohexyl-3-methyl-pentanol were obtained.

Workup

  1. customThe catalyst was removed
  2. distillationthe product distilled

Sources & evidence

ORD record
ord-74245e376ce243d8bf55cd9d2d5c3841
Source dataset
uspto-grants-2014_01
Patent number
US08623340B2

Reaction notes

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