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HRID467451

反应详情

EQUATION

反应方程式

HRID 467451 的结构方程式

REACTANTS

反应物

3
结构：O
HCID962

Water

H2O

结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@@H]3[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]32)C1
HCID908740

Epiandrosterone acetate

C21H32O3

PRODUCTS

生成物

1
结构：C[C@]12CC[C@H](O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12
HCID441302

Epiandrosterone

C19H30O2

收率 95%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A mixture of 5 (1 g, 3.00 mmol), NaOH 0.12 g (3.44 mmol) in methanol was refluxed for 10 min, cooled to room temperature and treated with water. The resulting precipitate was filtered off and washed with water to afford crude product 6 (0.82 g, 95%).

WORKUP

后处理

  1. temperaturewas refluxed for 10 min
  2. filtrationThe resulting precipitate was filtered off
  3. washwashed with water