HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Epiandrosterone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3beta-Acetoxy-5alpha-androstan-17-one | HCID 908740 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Epiandrosterone | HCID 441302 | 95% |
Reaction Steps
A mixture of 5 (1 g, 3.00 mmol), NaOH 0.12 g (3.44 mmol) in methanol was refluxed for 10 min, cooled to room temperature and treated with water. The resulting precipitate was filtered off and washed with water to afford crude product 6 (0.82 g, 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623849B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-ae5f46f7bef043fb87e21b3a77341060 |
| Source note | uspto-grants-2014_01 |