反应详情

To 2.4 g of 6-(4-methoxyphenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]thiazole in 200 ml methylene chloride was added 1.34 g of m-chloroperbenzoic acid in 150 ml of methylene chloride at ice-bath temperature. After 10 minutes the reaction mixture was diluted with methylene chloride and washed twice with 100 ml of 5 N sodium carbonate. Evaporation of the dried extracts left a solid which when recrystallized from chloroform-ether gave 1.6 g of the title product, m.p. 165°-170°.

1. washwashed twice with 100 ml of 5 N sodium carbonate
2. customEvaporation of the dried extracts
3. waitleft a solid which when
4. customrecrystallized from chloroform-ether