HuagongsheHuagongshe Chemistry Print Report · For research reference only
Prolinol → HCID 58548154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Prolinol | HCID 90908 | — |
| Reactant | 3-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acid | HCID 70098054 | — |
| Product | HCID 58548154 | HCID 58548154 | 29% |
Reaction Steps
According to the general method described in step 3 of example 53, reaction of 2-hydroxymethylpyrrolidine with 3-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acid provided the title compound as off-white solid (29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623866B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-cb5d74a0dc404cd3961cb3a894e231b6 |
| Source note | uspto-grants-2014_01 |