反应详情

A mixture of N-(tetrahydro-2H-pyran-4-yl)-N-[3-(trifluoromethoxy)benzyl]imidazo[1,2-a]pyridine-2-carboxamide (50 mg), 10% palladium-carbon (50 mg) and methanol (15 mL) was stirred in a nitrogen atmosphere for 2 hours at room temperature. The insoluble matter was filtered off and methanol was distilled off under reduced pressure to give the titled compound (48 mg).

1. filtrationThe insoluble matter was filtered off
2. distillationmethanol was distilled off under reduced pressure