反应详情

SEC is synthesized from L-cysteine hydrochloride (1.58 g, 0.01 mol) and ethyl bromide (1.09 g, 0.01 mol) with the following steps. The reaction mixture is diluted with water in a titration manner until a clear solution is formed. No more than necessary amount of water should be added to further dilute the mixture. Ammonia water was added to PH 9.5-10 with stirring at room temperature. After 2 hours reaction, the mixture is acidified with acetic acid to PH 5-5.5. The desired product was cooled in the refrigerator, filtered and washed successively with water and ethyl ether. The chemical structure of SEC is determined by Proton Nuclear Magnetic Resonance Spectroscopy.

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