HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nilutamide → HCID 49764092, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nilutamide | HCID 4493 | — |
| Reactant | HCID 46937259 | HCID 46937259 | — |
| Product | HCID 49764092 | HCID 49764092 | 67% |
Reaction Steps
The experimental protocol used is the same as that described for the synthesis of the compound of Example 2, intermediate 10.1 replacing 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-imidazolidine-2,4-dione. The expected compound is obtained in the form of a white solid with a yield of 67% (495 mg). Melting point: 130-131° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08624037B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-9a9c90681bf147f5b016f6704dfbcd29 |
| Source note | uspto-grants-2014_01 |