Alanine methyl ester hydrochloride → HCID 45111377, compound

Participants

Reaction Steps

Following the same procedure described for 16 and starting from (2S)-2-(4-{[4-(trifluoromethyl)-1,3-oxazol-2-yl]amino}phenyl)propanoic acid (19) (0.118 g, 0.39 mmol) and L-alanine methyl ester hydrochloride (0.035 g, 0.39 mmol), after workup and methyl ester hydrolysis, pure compound 24 (0.112 g, 0.29 mmol) was isolated as pale yellow oil (75%).

Provenance & Evidence