HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-tert-Butoxycarbonylamino-2-chloroisonicotinic acid → HCID 86674948, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-tert-Butoxycarbonylamino-2-chloroisonicotinic acid | HCID 10564144 | — |
| Reactant | 1-(5-Fluoro-2-methylphenyl)ethan-1-one | HCID 15335420 | — |
| Product | HCID 86674948 | HCID 86674948 | 24% |
Reaction Steps
The title compound was prepared following a procedure similar to example 121 using 5-(tert-butoxycarbonylamino)-2-chloroisonicotinic acid (505 mg, 1.85 mmol) and 5′-fluoro-2′-methylacetophenone (566 mg, 3.72 mmol) to afford the impure title compound as a beige solid (128 mg), used without further purification. LCMS: M+H+=289 & 291.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623889B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-ce8c7e5988fa43c395425994c5f715fa |
| Source note | uspto-grants-2014_01 |