1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → 1-(4-{[{[5-({Cyclopropyl[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino}methyl)furan-3-yl]carbonyl}(methyl)amino]methyl}benzyl)-N,N-dimethylpyrrolidine-3-carboxamide

Participants

Reaction Steps

The title compound was prepared according to general procedure BH using 5-({cyclopropyl[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino}methyl)furan-3-carboxylic acid (40 mg, 0.105 mmol), EDCI (28 mg, 0.158 mmol), HOBt (21 mg, 0.16 mmol), DIPEA (0.04 mL, 0.21 mmol), N,N-dimethyl-1-{4-[(methylamino)methyl]benzyl}pyrrolidine-3-carboxamide dihydrochloride (40 mg, 0.12 mmol) and DCM (5 mL).

Provenance & Evidence