HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 86630130, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 178418300 | HCID 178418300 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 86630130 | HCID 86630130 | — |
Reaction Steps
A solution of Fmoc-Xaa-OH (2 eq.), TBTU (2 eq.), HOBt (hydroxybenzotriazole) (2 eq.), DIEA (5.2 eq.) in NMP was added to the resin-bound free amine peptide and shaken for 60 min at room temperature and washed with NMP (5×).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08628750B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-5993e88ac0f047dfbfd4897d9fdb9bad |
| Source note | uspto-grants-2014_01 |