HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 86597653, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 86597653 | HCID 86597653 | — |
Reaction Steps
A solution of Fmoc-Xaa-OH (2 eq.), HATU (2 eq.), HOAt (hydroxyazobenzotriazole) (2 eq.), DIEA (4 eq.) in NMP was added to the resin-bound Nα-methylamine free peptides and shaken for 3 hours at room temperature and washed with NMP (5×).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08628750B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-4300a2d9fdd840ada7a3b44f5efd5124 |
| Source note | uspto-grants-2014_01 |