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HRID469139

反应详情

EQUATION

反应方程式

HRID 469139 的结构方程式

REACTANTS

反应物

2
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F
HCID9886157

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)

C10H15F6N6OP

PRODUCTS

生成物

1
结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.On1nnc2cccnc21
HCID86597653

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN1CCCC1=O
溶剂HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

PROCEDURE

实验过程

A solution of Fmoc-Xaa-OH (2 eq.), HATU (2 eq.), HOAt (hydroxyazobenzotriazole) (2 eq.), DIEA (4 eq.) in NMP was added to the resin-bound Nα-methylamine free peptides and shaken for 3 hours at room temperature and washed with NMP (5×).

WORKUP

后处理

  1. washwashed with NMP (5×)