HRID4692

反应详情

EQUATION

反应方程式

HRID 4692 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

CONDITIONS

反应条件

温度
10 °C

PROCEDURE

实验过程

A mixture of 6-methyl-5-(4-formylpiperazin-1-ylmethyl)-4-(3-nitrophenyl)-2-phenylpyrimidine (4.5 g) and hydrochloric acid (2 ml) in methyl alcohol (45 ml) was stirred at 10° C. for 2 hours. The resulting precipitates were collected by filtration, washed with methyl alcohol and dried in vacuo to give 6-methyl-5-(4-formylpiperazin-1-ylmethyl)-4-(3-nitrophenyl)-2-phenylpyrimidine hydrochloride (4.14 g).

WORKUP

后处理

  1. customThe resulting precipitates
  2. filtrationwere collected by filtration
  3. washwashed with methyl alcohol
  4. customdried in vacuo