Thionyl Chloride → 3-Bromo-4-fluorobenzoyl chloride

HRID 469332Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 469332
[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5](O)=[O:6].S(Cl)([Cl:14])=O>>[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5]([Cl:14])=[O:6]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 705093-Bromo-4-fluorobenzoic acid

Produkt 1

HCID 695983-Bromo-4-fluorobenzoyl chloride

Versuchsvorschrift

2.17 g (9.41 mmol) 3-bromo-4-fluorobenzoic acid were mixed with 20 mL thionyl chloride and then boiled for 2 h. The reaction mixture was evaporated to dryness and coevaporated twice with toluene. The residue was reacted further as the crude product.

Aufarbeitung

  1. customThe reaction mixture was evaporated to dryness
  2. customThe residue was reacted further as the crude product

Quellen und Nachweise

ORD-Eintrag
ord-b8ace32349b54da58a96b7c11a9daa56
Quelldatensatz
uspto-grants-2014_01
Patentnummer
US08629137B2

Notizen zur Reaktion

Wird geladen…