HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Bromo-4-fluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Bromo-4-fluorobenzoic acid | HCID 70509 | — |
| Product | 3-Bromo-4-fluorobenzoyl chloride | HCID 69598 | — |
Reaction Steps
2.17 g (9.41 mmol) 3-bromo-4-fluorobenzoic acid were mixed with 20 mL thionyl chloride and then boiled for 2 h. The reaction mixture was evaporated to dryness and coevaporated twice with toluene. The residue was reacted further as the crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629137B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-b8ace32349b54da58a96b7c11a9daa56 |
| Source note | uspto-grants-2014_01 |