HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Cyano-3-fluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Cyano-3-fluorobenzoic acid | HCID 2778468 | — |
| Product | 4-Cyano-3-fluorobenzoyl chloride | HCID 19956739 | — |
Reaction Steps
0.66 g (4.0 mmol) 4-cyano-3-fluoro-benzoic acid were mixed with 10 mL thionyl chloride and boiled for 2 h. The mixture was evaporated to dryness and coevaporated twice with toluene. The residue was reacted further as the crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629137B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-5d904c35d39c4e24855c8b7d93a46084 |
| Source note | uspto-grants-2014_01 |