HCID 59856530, compound → HCID 59856532, compound

Participants

Reaction Steps

14.4 g (40.3 mmol) (1-benzyl-piperidin-4-yl)-[2-(3-fluoro-2-nitro-phenyl)-ethyl]-amine in 100 mL MeOH were stirred with 2.00 g rhodium charcoal (10%) and shaken at RT under a hydrogen atmosphere (3 bar). The catalyst was filtered off and the solvent was eliminated i. vac. The residue was further reacted immediately as the crude product.

Provenance & Evidence