HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 25271153, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-(Piperidin-4-yl)quinolin-2(1H)-one | HCID 18321046 | — |
| Reactant | 6-(6-chloropyrimidine-4-carbonyl)-3,4-dimethyl-3H-benzoxazol-2-one | HCID 58181162 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 25271153 | HCID 25271153 | — |
Reaction Steps
60 mg (0.26 mmol) 3-piperidin-4-yl-1H-quinolin-2-one, 80 mg (0.26 mmol) 6-(6-chloropyrimidine-4-carbonyl)-3,4-dimethyl-3H-benzoxazol-2-one and 0.15 mL (0.86 mmol) DIPEA were combined in 3 mL DMF and stirred overnight at RT. The reaction mixture was added to water and the precipitate formed was suction filtered, washed with MeOH and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629137B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-e157e1b00ffd4cc588b23595d5890327 |
| Source note | uspto-grants-2014_01 |