HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-amino-2-thiophenecarboxylate → HCID 58557000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-amino-2-thiophenecarboxylate | HCID 89652 | — |
| Reactant | Ethyl 2-bromo-2-phenylacetic acid | HCID 19431595 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 58557000 | HCID 58557000 | — |
Reaction Steps
A solution of ethyl 2-bromo-2-phenylacetic acid (600 mg, 2.79 mmol) and methyl 3-aminothiophene-2-carboxylate (438 mg, 2.79 mmol) in acetonitrile (20 ml) was heated under microwave irradiation at 100° C. for 1 hour. Acetonitrile was evaporated to dryness and the resulting residue was used in the next step without any further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629160B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-2852a2337e8d4caaa243ffaee22e39b6 |
| Source note | uspto-grants-2014_01 |