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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469552Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 53237966, compound

https://huagongshe.com/reaction/469552

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReactantHCID 67161481HCID 67161481—
ProductHCID 53237966HCID 53237966—

Reaction Steps

The product from Example 35E and 2-(3,5-difluorophenyl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 3.75 (s, 2H) 7.03-7.20 (m, 3H) 7.38 (dd, J=9.46, 2.44 Hz, 1H) 7.52-7.68 (m, 5H) 7.82 (d, J=2.44 Hz, 1H) 8.48 (d, J=3.36 Hz, 1H); MS (ESI) m/z 410 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629143B2
Source datasetuspto-grants-2014_01
ORD IDord-72eca1e9353948f4a0a1ac0a1a802aa2
Source noteuspto-grants-2014_01