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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469555Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 53237969, compound

https://huagongshe.com/reaction/469555

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant2-Amino-4-methyl-1(2H)-phthalazinoneHCID 819574—
ProductHCID 53237969HCID 53237969—

Reaction Steps

The product from Example 28A and 2-(3,5-difluorophenyl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 11.58-11.61 (m, 1H), 8.32 (d, J=7.9 Hz, 1H), 8.00-8.02 (m, 2H), 7.90-7.93 (m, 1H), 7.09-7.21 (m, 2H), 7.02-7.05 (m, 1H), 3.74 (s, 2H), 2.55 (s, 3H); MS (ESI) m/z 330 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629143B2
Source datasetuspto-grants-2014_01
ORD IDord-26450202992141a89bdb81c45a40e8d0
Source noteuspto-grants-2014_01