HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58127025, compound → HCID 67160458, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58127025 | HCID 58127025 | — |
| Reactant | 2-amino-4-(trifluoromethyl)phthalazin-1(2H)-one | HCID 67161111 | — |
| Product | HCID 67160458 | HCID 67160458 | — |
Reaction Steps
The product of Example 11B and 2-(4-chloro-3-fluorophenyl)acetyl chloride were treated using a method similar to that described in Example 1C to give the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 11.92-11.95 (bs, 1H), 8.43 (d, J=8.3 Hz, 1H), 8.11-8.17 (m, 1H), 7.99-8.08 (m, 2H), 7.58 (t, J=8.1 Hz, 1H), 7.43 (dd, J=10.5, 1.9 Hz, 1H), 7.25 (dd, J=8.3, 1.9 Hz, 1H), 3.79 (s, 2H); MS (ESI) m/z 400 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629143B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-c89122c321f7485498dbf6096cebc6d3 |
| Source note | uspto-grants-2014_01 |