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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469616Generated: October 30, 2026

1-Adamantaneacetic acid → HCID 53238434, compound

https://huagongshe.com/reaction/469616

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Adamantaneacetic acidHCID 123221—
Reactant2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-oneHCID 67161367—
ProductHCID 53238434HCID 53238434—

Reaction Steps

The product of Example 86A and 2-(adamantan-1-yl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.18-11.35 (bs, 1H), 8.39-8.42 (m, 1H), 7.89-8.02 (m, 2H), 7.70-7.73 (m, 1H), 7.56-7.68 (m, 4H), 2.04 (s, 2H), 1.92-1.95 (m, 3H), 1.66-1.69 (m, 6H), 1.63-1.70 (m, 3H), 1.57-1.62 (m, 3H); MS (ESI+) m/z 448 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629143B2
Source datasetuspto-grants-2014_01
ORD IDord-5579eb0b3e9f4a80855806acfbbfeb57
Source noteuspto-grants-2014_01