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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469618Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 67161293, compound

https://huagongshe.com/reaction/469618

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-oneHCID 67161367—
ProductHCID 67161293HCID 67161293—

Reaction Steps

The product of Example 86A and 2-(3,5-difluorophenyl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.77-11.78 (bs, 1H), 8.39-8.42 (m, 1H), 7.89-8.03 (m, 2H), 7.69-7.74 (m, 1H), 7.60-7.65 (m, 4H), 7.06-7.20 (m, 3H), 3.76 (s, 2H); MS (ESI+) m/z 426 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629143B2
Source datasetuspto-grants-2014_01
ORD IDord-3e30f822589d49ebab4f4e01a2d01305
Source noteuspto-grants-2014_01