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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469653Generated: October 29, 2026

3,5-Difluorophenylacetic acid → HCID 53236391, compound

https://huagongshe.com/reaction/469653

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReactantHCID 67160611HCID 67160611—
ProductHCID 53236391HCID 53236391—

Reaction Steps

The product of Example 163A and 2-(3,5-difluorophenyl)acetic acid were treated using a method similar to that described in Example 17C to give the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.74 (s, 1H), 8.39-8.42 (m, 1H), 7.89-8.02 (m, 2H), 7.74-7.77 (m, 1H), 7.25-7.39 (m, 3H), 7.12-7.18 (m, 3H), 3.77 (s, 2H), 2.32 (s, 3H), 2.31 (s, 3H); MS (APCI+) M/Z 420 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629143B2
Source datasetuspto-grants-2014_01
ORD IDord-0e3bb4e220094ef9b3130422c6deb6f4
Source noteuspto-grants-2014_01