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0 °C

To a solution of hydroxypivalic acid methyl ester (4 mL, 31.36 mmol) in dichloromethane (20 mL) is added 3,4-dihydro-2H-pyran (5.84 mL, 63.99 mmol). The reaction mixture is cooled to 0° C. and sulfuric acid on silica gel (125 mg, 0.2 mL sulfuric acid/10 g silica gel) is added and the reaction mixture is stirred at room temperature for 25 minutes. After this time, the reaction mixture is filtered through a glass funnel and concentrated under reduced pressure to yield the title compound. It is used without purification.

1. filtrationAfter this time, the reaction mixture is filtered through a glass funnel
2. concentrationconcentrated under reduced pressure