HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Cyclopent-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 5-cyclopent-1-enyl-N-pyridin-3-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Cyclopent-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 15486611 | — |
| Reactant | 5-Iodo-N-(pyridin-3-yl)-6-(2,2,2-trifluoroethoxy)nicotinamide | HCID 71294362 | — |
| Product | 5-cyclopent-1-enyl-N-pyridin-3-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide | HCID 71294112 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1c using 5-iodo-N-(pyridin-3-yl)-6-(2,2,2-trifluoroethoxy)nicotinamide (Example 1b) and 2-(1-cyclopenten-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAN 287944-10-9) as starting materials; MS (ESI) 364.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629166B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-86c217c312484c519c2d4a2c13cc446b |
| Source note | uspto-grants-2014_01 |