Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469781Generated: October 25, 2026

2-Aminopyridine → 5-cyclopentyl-N-pyridin-2-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide

https://huagongshe.com/reaction/469781

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminopyridineHCID 10439—
Reactant5-Cyclopentyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acidHCID 71294186—
Product5-cyclopentyl-N-pyridin-2-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamideHCID 71294560—

Reaction Steps

The title compound was synthesized in analogy to Example 1b using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 9c) and 2-pyridinamine (CAN 504-29-0) as starting materials; MS (ESI) 366.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629166B2
Source datasetuspto-grants-2014_01
ORD IDord-bcb3cf8396ea4f15ae5e79638a491250
Source noteuspto-grants-2014_01