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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469796Generated: October 29, 2026

4-Aminopyrimidine → HCID 71294419, compound

https://huagongshe.com/reaction/469796

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminopyrimidineHCID 68958—
Reactant5-Cyclopentyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acidHCID 71294186—
ProductHCID 71294419HCID 71294419—

Reaction Steps

This compound was prepared following the same procedure as described in Example 11 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 9c) (100 mg, 0.35 mmol) and 4-pyrimidinamine (CAN 591-54-8, 39.5 mg, 0.41 mmol) as starting materials; off white solid (63 mg, 49.7%). MS (ESI): 367.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629166B2
Source datasetuspto-grants-2014_01
ORD IDord-3082118158b047de914ae7066f17bb32
Source noteuspto-grants-2014_01