HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 1013643-07-6
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 53416660 | HCID 53416660 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1013643-07-6 | HCID 86762217 | — |
Reaction Steps
A solution of 5.3 g (22.7 mmol) 2-bromo-4-nitro-pyridin-3-ol in 100 ml MeOH:THF=1:2 is hydrogenated in the presence of 0.5 g Pt/C (5%, Engelhard 4709). The reaction mixture is filtered (2 glass fiber filters used) and the filtrate is concentrated in vacuo to afford the crude title compound as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629168B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-39337ffe6abd4520b32a4ed1f6a102d3 |
| Source note | uspto-grants-2014_01 |