HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → HCID 20384873, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 1,1,1,3,3,3-Hexafluoro-2-(4-(methylamino)phenyl)propan-2-OL | HCID 805015 | — |
| Reactant | Acetyl isothiocyanate, chloro- | HCID 10997087 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 20384873 | HCID 20384873 | — |
Reaction Steps
To p-(hexafluoro-2-hydroxy-2-propyl)-N-methylaniline (2.73 gm., 0.01 mole) in dimethoxyethane (40 ml), add chloroacetyl isothiocyanate (1.50 gm., 0.011 mole) and stir 1 hr. Pour the reaction mixture onto water and neutralize with sodium bicarbonate. Extract with ether, dry and concentrate. Recrystallize from ether to obtain the product, m.p. 240°-242° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04176120 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-8cfe4bd7f8854d08b3351abc773bd256 |
| Source note | uspto-grants-1979_11 |