反应详情

To p-(hexafluoro-2-hydroxy-2-propyl)-N-methylaniline (2.73 gm., 0.01 mole) in dimethoxyethane (40 ml), add chloroacetyl isothiocyanate (1.50 gm., 0.011 mole) and stir 1 hr. Pour the reaction mixture onto water and neutralize with sodium bicarbonate. Extract with ether, dry and concentrate. Recrystallize from ether to obtain the product, m.p. 240°-242° C.

1. additionPour the reaction mixture onto water
2. extractionExtract with ether
3. customdry
4. concentrationconcentrate
5. customRecrystallize from ether
6. customto obtain the product, m.p. 240°-242° C.