HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 5,6-Dimethoxy-3[4(tetrahydropyran-2-carbonyl) piperazinyl]methylene oxindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | (Oxan-2-yl)(piperazin-1-yl)methanone | HCID 20385082 | — |
| Reactant | HCID 178486553 | HCID 178486553 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 5,6-Dimethoxy-3[4(tetrahydropyran-2-carbonyl) piperazinyl]methylene oxindole | HCID 53824958 | — |
Reaction Steps
5.00 g. of 5,6-dimethoxy-3-hydroxymethylene oxindole, 5,6 g. 1-(tetrahydropyran-2-carbonyl)piperazine and 2.1 g. acetic acid in 60 ml. benzene was reacted as described in Example 5 to give 6.18 g. of product, m.p. 208°-210° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04176191 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-e9a52141d2cb4fb888125a14c055a68c |
| Source note | uspto-grants-1979_11 |