Allyl(4-methylphenyl) sulfide → HCID 14154894, compound

HRID 4709Notes

Reaction equation

HRID 4709 reaction equation
[N:1]1([CH2:6][C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=2)=[N+:8]([O-:10])[CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1.[CH3:19][C:20]1[CH:25]=[CH:24][C:23]([S:26][CH2:27][CH:28]=[CH2:29])=[CH:22][CH:21]=1>>[CH3:18][O:17][C:13]1[CH:12]=[C:11]([C:7]2([CH2:6][N:1]3[CH:5]=[CH:4][N:3]=[CH:2]3)[CH2:29][CH:28]([CH2:27][S:26][C:23]3[CH:22]=[CH:21][C:20]([CH3:19])=[CH:25][CH:24]=3)[O:10][N:8]2[CH3:9])[CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 232029Allyl(4-methylphenyl) sulfideHCID 131715454HCID 131715454, compound

Product 1

HCID 14154894HCID 14154894, compound

Procedure

The title compound was prepared by a procedure similar to that described in Example 1 by reacting 2-(1H-imidazol-1-yl)-1-(3-methoxyphenyl)-N-methylethanimine N-oxide (1, R1 =3--OCH3) with allyl 4-methyphenyl sulfide (2: R2 =4--CH3). The resulting cis- and trans-diastereomeric mixture of compound 3 (R1 =3--OCH3, R2 =4--CH3, n=0) was flash-chromatographed on neutral silica gel using ethyl acetate as eluent.

Workup

  1. customwas flash-chromatographed on neutral silica gel

Sources & evidence

ORD record
ord-93b72a32055f4663a84ab26eb7211fd7
Source dataset
uspto-grants-1988_02
Patent number
US04727156

Reaction notes

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