反应详情

Sodium azide (1.176 g) was added to a suspension of 5-(benzyloxy)-8-(2-chloroacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one (example 11, step e) (4.8 g) in DMF (50 mL) and stirred for 2 h. The mixture was poured onto ice/water and the resulting solid collected by filtration, washed with water and dried under vacuum at 40° C. to afford the subtitled compound as a light brown solid. Yield 4.6 g.

1. additionThe mixture was poured onto ice/water
2. filtrationthe resulting solid collected by filtration
3. washwashed with water
4. customdried under vacuum at 40° C.