HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Bromopropyl)diethylamine hydrobromide → 7,7-Dimethyl-2-cyclopropyl-5-(3-diethylamino-propyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Bromopropyl)diethylamine hydrobromide | HCID 12639158 | — |
| Reactant | 7,7-dimethyl-2-cyclopropyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione hydrochloride | HCID 70609830 | — |
| Product | 7,7-Dimethyl-2-cyclopropyl-5-(3-diethylamino-propyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione | HCID 70611122 | — |
Reaction Steps
Prepared analogous to Example 23 from 2.45 gm of 7,7-dimethyl-2-cyclopropyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione hydrochloride and 2.3 gm of 3-diethylamino-propyl bromide hydrobromide. The crude product was purified by chromatography on a silicagel column (eluant: chloroform with increasing content of acetone).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04176184 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-e2ef9d45951040e392ad9e691da19a6c |
| Source note | uspto-grants-1979_11 |