HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron trifluoride etherate → Nabilone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | 5-(1,1-Dimethylheptyl)resorcinol | HCID 91870 | — |
| Reactant | HCID 20333900 | HCID 20333900 | — |
| Product | Nabilone | HCID 5284592 | — |
Reaction Steps
Following the same procedure as set forth above, (+)-6,6-dimethyl-2,2-diacetoxy-3-norpinene was reacted with 5-(1,1-dimethylheptyl)resorcinol in the presence of boron trifluoride diethyl etherate to afford (-)-trans-1-hydroxy-3-(1,1-dimethylheptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04176233 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-051c6af4283c454d994347d63b60ad33 |
| Source note | uspto-grants-1979_11 |