化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → 5-ethynyl-N-methylpyridin-2-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Methyl-(5-trimethylsilanylethynyl-pyridin-2-yl)-amine | HCID 66705950 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 5-ethynyl-N-methylpyridin-2-amine | HCID 22663128 | — |
反応手順
The title compound is synthesized according to general procedure GP3 starting from 1.5 g (7.3 mmol) methyl-(5-trimethylsilanylethynyl-pyridin-2-yl)-amine and 507 mg (3.7 mmol) K2CO3 in 10 mL MeOH. Yield: 698 mg (56%) after chromatography on silica gel.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08633183B2 |
| 出典データセット | uspto-grants-2014_01 |
| ORD ID | ord-4abaf2844fc741e9ab769aaf5d22b918 |
| 出典メモ | uspto-grants-2014_01 |