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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 471429Generated: October 31, 2026

HCID 86703876, compound → HCID 86703875, compound

https://huagongshe.com/reaction/471429

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86703876HCID 86703876—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 86703875HCID 8670387599.8%

Reaction Steps

2-(4-Benzyloxy-2-methoxy-phenyl)-trans-cyclopropanecarboxylic acid methyl ester (500 mg, 1.6 mmol) is dissolved in ethyl acetate (10 mL) and hydrogenated for 2 hours in a Parr apparatus at 1 bar using 10% Pd/C as the catalyst. The solution is filtered through celite and the solvent removed under vacuum to give the title compound (yield 355 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633182B2
Source datasetuspto-grants-2014_01
ORD IDord-2785889bd92a41d294f1acb87f01aa10
Source noteuspto-grants-2014_01