HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86703876, compound → HCID 86703875, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86703876 | HCID 86703876 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86703875 | HCID 86703875 | 99.8% |
Reaction Steps
2-(4-Benzyloxy-2-methoxy-phenyl)-trans-cyclopropanecarboxylic acid methyl ester (500 mg, 1.6 mmol) is dissolved in ethyl acetate (10 mL) and hydrogenated for 2 hours in a Parr apparatus at 1 bar using 10% Pd/C as the catalyst. The solution is filtered through celite and the solvent removed under vacuum to give the title compound (yield 355 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633182B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-2785889bd92a41d294f1acb87f01aa10 |
| Source note | uspto-grants-2014_01 |