反应详情

4-Nitro-N-(2-hydroxy-2-methyl-propyl)-3,5-dimethyl-benzamide (1.2 g, 4.51 mmol) is suspended in methanol (10 mL) and hydrogenated at 3 bar for 3 hours using 10% palladium on activated carbon (120 mg) as the catalyst. The mixture is filtered through celite and the solvent removed under vacuum to give the title compound (Yield 900 mg).

1. filtrationThe mixture is filtered through celite
2. customthe solvent removed under vacuum