4-(Methylthio)butanol → 2-(4-(Methylthio)butoxy)-6-nitrobenzonitrile

HRID 471741Notes

Reaction equation

[CH3:1][S:2][CH2:3][CH2:4][CH2:5][CH2:6][OH:7].[N+:8]([C:11]1[CH:18]=[CH:17][CH:16]=[C:15]([N+]([O-])=O)[C:12]=1[C:13]#[N:14])([O-:10])=[O:9]>>[CH3:1][S:2][CH2:3][CH2:4][CH2:5][CH2:6][O:7][C:15]1[CH:16]=[CH:17][CH:18]=[C:11]([N+:8]([O-:10])=[O:9])[C:12]=1[C:13]#[N:14]

Participants

Reactant 2

HCID 5197934-(Methylthio)butanol

HCID 520718Dinitrobenzonitrile

Product 1

HCID 667473832-(4-(Methylthio)butoxy)-6-nitrobenzonitrileYield 89%

Procedure

Prepared as in Example 215c from 4-(methylthio)butan-1-ol and 2,6-dinitrobenzonitrile in 89% yield. MS 267 (MH+).

Sources & evidence

ORD record: ord-0e4d1f2844094324bf263b23081785c6
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08633186B2

Reaction notes

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